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The principal areas of core R&D carried out at ACERT are
(click on the underlined text to get the most recent/important information)
Pulsed ESR: Distance Measurements in proteins and aggregates using double quantum coherence (DQC) ESR, to advance our knowledge of structure and function of biomolecules using longer distance constraints, provided by site-directed spin labeling and pulsed ESR distance measurements.
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Pulsed ESR: pulsed 2D Fourier transform ESR , to further develop 2D-ELDOR in the study of the dynamic structure of membranes and of proteins, as well as lipid-protein interactions.
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High Resolution ESR microscopy , to establish cw and pulse ESR micro-imaging for biomedical studies of tissues, cells and other bio-samples with micron resolution.
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HFHF ESR: continuous-wave , to further develop quasi-optical techniques for HFHF-ESR to unravel the complex dynamics in biological systems and, especially, to extend high power pulsed ESR to the mm-wave regime, to benefit from the improved orientational resolution and faster .snapshot. feature at higher frequencies.
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HFHF ESR: time-domain , to further develop quasi-optical techniques for HFHF-ESR to unravel the complex dynamics in biological systems and, especially, to extend high power pulsed ESR to the mm-wave regime, to benefit from the improved orientational resolution and faster .snapshot. feature at higher frequencies.
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Multifrequency Studies , to advance knowledge of dynamics in proteins, DNA, and membranes by a mixture of multifrequency and multidimensional ESR.
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Protein Dynamics by NMR
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Model and Cell Membrane Dynamics by ESR
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Theory and computational methods , to improve the methods for interpreting multifrequency spectra in terms of powerful algorithms based on the stochastic Liouville equation and on molecular dynamics simulations.
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ACERT's Collaborative Projects cover a wide range of biomedical research areas, emphasizing the central role that modern ESR methods can play in contemporary biomedical sciences.
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Recent Highlights
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Full Highlights Archive
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