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The National Biomedical Research Center for AdvanCed ESR Technology (ACERT) is an outgrowth of extensive experience in developing the methods of modern electron spin resonance (ESR, a.k.a. EPR-Electron Paramagnetic Resonance) by Prof. Jack H. Freed’s research group at Cornell University. The technologies upon which this Center is based are in many respects unique in the world. These principal areas of our expertise are:
Pulsed Fourier Transform and Two Dimensional ESR
- Distance Measurements in Proteins and Aggregates using Double Quantum Coherence ESR and Related Methods;
- Dynamic Structure of Membranes and Proteins by 2D-ELDOR;
- Functional Dynamics of Proteins by Time Resolved FT and 2D-ESR;
High Frequency-High Field (HFHF) ESR
- New Instrumental Developments in HFHF ESR;
- Development of High Power Pulsed HFHF ESR;
- Multifrequency Studies of Dynamics in Proteins and Membranes.
High Resolution ESR Microscopy
- Development of Continuous Wave and Pulsed ESR Microscopes
- Biomedical Applications of ESR Micro-Imaging
Theory and Computational Methods for Modern ESR
- Improved Theoretical and Computational Methods for Analyzing Modern ESR Experiments.
In addition to making resources available to the biomedical community, publishing and advertising results, and running workshops on the new methodologies, ACERT also addresses the need to bring these new technologies to other laboratories.
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