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National Biomedical Resource
for Advanced Electron Spin Resonance Spectroscopy

Our research is supported by grant 1R24GM146107 from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health.

  Key publications
Pulsed Two-Dimensional ESR
Articles:

Focus: Two-dimensional electron-electron double resonance and molecular motions: The challenge of higher frequencies
J.M. Franck, S. Chandrasekaran, B. Dzikovski, C.R. Dunnam, and J.H. Freed.
J. Chem. Phys. 142, 212302-212314 (2015).
<doi:10.1063/1.4917322>
PMID: 26049420      PMCID: PMC4443839
 

Molecular Motions
S.K. Misra and J.H. Freed.
In Multifrequency Electron Paramagnetic Resonance, S.K. Misra, Ed.
Wiley-VCH: New York, 2011; Chapter 11, pp. 497-544.
PMID: [None - Book]      PMCID: [None - Book]
 

2D-ELDOR Study of Heterogeneity and Domain Structure Changes in Plasma Membrane Vesicles upon Cross-Linking of Receptors
Y.-W. Chiang, A.J. Costa-Filho, B. Baird, and J.H. Freed.
J. Phys. Chem. B 115, 10462-10469 (2011).
Supporting Information
<doi:10.1021/jp2016243>
PMID: 21780815      PMCID: PMC3165081
 

Calculation of Double-Quantum-Coherence Two-dimensional Spectra: Distance Measurements and Orientational Correlations
S.K. Misra, P.P. Borbat, J.H. Freed.
Appl. Magn. Reson. 36, 237-258 (2009).
<doi:10.1007/s00723-009-0023-5>
PMID: 20161423      PMCID: PMC2786184
 

Dynamic Molecular Structure and Phase Diagram of DPPC-Cholesterol Binary Mixtures: A 2D-ELDOR Study
Y.-W. Chiang, A.J. Costa-Filho, and J.H. Freed.
J. Phys. Chem. B 111, 11260-11270 (2007).
Supporting Information
<doi:10.1021/jp0732110>
PMID: 17760438     
 

2D-ELDOR Using Full Sc- Fitting and Absorption Lineshapes
Y.-W. Chiang, A. Costa-Filho, J.H. Freed.
J. Magn. Reson. 188, 231-245 (2007).
<doi:10.1016/j.jmr.2007.06.014>
PMID: 17681478     
 

Two-Dimensional ELDOR in the Study of Model and Biological Membranes
Y.-W. Chiang, A.J. Costa-Filho, and J.H. Freed.
Appl. Magn. Reson. 31, 375-386 (2007).
 

Collective Fluctuations in Ordered Fluids Investigated by Two-Dimensional Electron-Electron Double Resonance Spectroscopy
B. Fresch, D. Frezzato, G.J. Moro, G. Kothe, and J.H. Freed.
J. Phys. Chem. B 110, 24238-24254, (2006).
<doi:10.1021/jp064028u>
PMID: 17125397     
 

High-Frequency ESR at ACERT
K.A. Earle, B. Dzikovski, W. Hofbauer, J.K. Moscicki and J.H. Freed.
Magn. Reson. Chem. 43, S256-S266 (2005).
<doi:10.1002/mrc.1684>
PMID: 16235203     
 

High-Power 95 GHz Pulsed Electron Spin Resonance Spectrometer
W. Hofbauer, K.A. Earle, C.R. Dunnam, J.K. Moscicki, and J.H. Freed.
Rev. Sci. Instrum. 75, 1194-1208 (2004).
<doi:10.1063/1.1710700>
 

Lipid-Gramicidin Interactions: Dynamic Structure of the Boundary Lipid by 2D-ELDOR
A.J. Costa-Filho, R.H. Crepeau, P.P. Borbat, M. Ge, and J. H. Freed.
Biophys. J. 84, 3364-3378 (2003).
<doi:10.1016/S0006-3495(03)70060-5>
PMID: 12719265      PMCID: PMC1302896
 

A 2D-ELDOR Study of the Liquid Ordered Phase in Multilamellar Vesicle Membranes
A.J. Costa-Filho, Y. Shimoyama, and J.H. Freed.
Biophys. J. 84, 2619-2633, (2003).
<doi:10.1016/S0006-3495(03)75067-X>
PMID: 12668470      PMCID: PMC1302828
 

Nanosecond RF Switch Driver
C. Dunnam.
Patent #5,214,315, May 25, 1993