SARS-CoV-2 Fusion Peptide has a Greater Membrane Perturbating Effect than SARS-CoV with Highly Specific Dependence on Ca²⁺
A. L. Lai and J. H. Freed.
J. Mol. Biol. 433, 166946 (2021)
<doi:10.1016/j.jmb.2021.166946>
PMID: 33744314      PMCID: PMC7969826
 

Microsecond dynamics in proteins by two-dimensional ESR. II. Addressing computational challenges
P. Gupta, K. Chaudhari, and J. H. Freed.
J. Chem. Phys. 154, 084115 (2021)
Supporting Information
<doi:10.1063/5.0042441>
PMID: 33639766      PMCID: PMC7928224
 

Microsecond Exchange Processes Studied by Two-Dimensional ESR at 95 GHz
B. Dzikovski, V. V. Khramtsov, S. Chandrasekaran, C. Dunnam, M. Shah, and J. H. Freed.
J. Am. Chem. Soc. 142, 21368-21381 (2020)
Supporting Information
<doi:10.1021/jacs.0c09469>
PMID: 33305945      PMCID: PMC7810061
 

Engineered chemotaxis core signaling units indicate a constrained kinase-off state
A. R. Muok, T. K. Chua, M. Srivastava, W. Yang, Z. Maschmann, P. P. Borbat, J. Chong, S. Zhang, J. H. Freed, A. Briegel, B. R. Crane.
Sci. Signal. 13, eabc1328 (2020)
Supporting Information
<doi:10.1126/scisignal.abc1328>
PMID: 33172954      PMCID: PMC7790435
 

Structural Dynamics by NMR in the Solid State: The Unified MOMD Perspective Applied to Organic Frameworks with Interlocked Molecules
E. Meirovitch, Z. Liang, and J. H. Freed.
J. Phys. Chem. B 124, 6225-6235 (2020)
Supporting Information
<doi:10.1021/acs.jpcb.0c03687>
PMID: 32584038      PMCID: PMC7666760
 

Conformational Dynamics in Extended RGD-Containing Peptides
W. R. Lindemann, A. J. Mijalis, J. L. Alonso, P. P. Borbat, J. H. Freed, M. A. Arnaout, B. L. Pentelute, and J. H. Ortony.
Biomacromolecules 21, 2786-2794 (2020)
Supporting Information
<doi:10.1021/acs.biomac.0c00506>
PMID: 32469507      PMCID: PMC7388056
 

Microsecond dynamics in proteins by two-dimensional ESR: Predictions
P. Gupta, Z. Liang, and J. H. Freed.
J. Chem. Phys. 152, 214112 (2020)
Supporting Information
<doi:10.1063/5.0008094>
PMID: 32505151      PMCID: PMC7863697
 

George K. Fraenkel, Electron Spin Resonance Pioneer
J.H. Freed.
In Pioneers of Magnetic Resonance. Strom, E. T., Mainz, V. V., Eds.   American Chemical Society: Washington, DC, ACS Symposium Series, 2020; Volume 1349, Chapter 8, pp. 137-154.
<doi:10.1021/bk-2020-1349.ch008>
PMID: None-book      PMCID: None-book
 

High-yield production in E. coli and characterization of full-length functional p13^II protein from human T-cell leukemia virus type 1
E. R. Georgieva, P. P. Borbat, C. Fanouraki, J. H. Freed.
Protein Expr. Purif. 173, 105659 (2020)
Supporting Information
<doi:10.1016/j.pep.2020.105659>
PMID: 32360379      PMCID: PMC7266171
 

Ca²⁺ Ions Promote Fusion of Middle East Respiratory Syndrome Coronavirus with Host Cells and Increase Infectivity
M. R. Straus, T. Tang, A. L. Lai, A. Flegel, M. Bidon, J. H. Freed, S. Daniel, G. R. Whittaker.
J. Virol. 94, e00426-20 (2020)
Supporting Information
<doi:10.1128/JVI.00426-20>
PMID: 32295925      PMCID: PMC7307142
 

Calcium Ions Directly Interact with the Ebola Virus Fusion Peptide To Promote Structure-Function Changes That Enhance Infection
L. Nathan, A. L. Lai, J. K. Millet, M. R. Straus, J. H. Freed, G. R. Whittaker, and S. Daniel.
ACS Infect. Dis. 6, 250-260 (2020)
Supporting Information
<doi:10.1021/acsinfecdis.9b00296>
PMID: 31746195      PMCID: PMC7040957
 

Local ordering and dynamics in anisotropic media by magnetic resonance: from liquid crystals to proteins
E. Meirovitch & J. H. Freed.
Liq. Cryst. 47, 1926-1954 (2020)
<doi:10.1080/02678292.2019.1622158>
PMID: 32435078      PMCID: PMC7239324
 

The asymmetric function of Dph1–Dph2 heterodimer in diphthamide biosynthesis
M. Dong, E. E. Dando, I. Kotliar, X. Su, B. Dzikovski, J. H. Freed, and H. Lin.
J. Biol. Inorg. Chem. 24, 777-782 (2019)
<doi:10.1007/s00775-019-01702-0>
PMID: 31463593      PMCID: PMC6893874
 

Insights into histidine kinase activation mechanisms from the monomeric blue light sensor EL346
I. Dikiy, U. R. Edupuganti, R. R. Abzalimov, P. P. Borbat, M. Srivastava, J. H. Freed, and K. H. Gardner.
Proc. Natl. Acad. Sci. 116, 4963-4972 (2019)
Supporting Information
<doi:10.1073/pnas.1813586116>
PMID: 30808807      PMCID: PMC6421462
 

Comment on "Distinct Populations in Spin-Label EPR Spectra from Nitroxides."
E. Meirovitch, B. Dzikovski, and J. H. Freed.
J. Phys. Chem. B 123, 2454-2456 (2019)
Supporting Information
<doi:10.1021/acs.jpcb.8b07730>
PMID: 30768266      PMCID: PMC6497408
 

Singular Value Decomposition Method To Determine Distance Distributions in Pulsed Dipolar Electron Spin Resonance: II. Estimating Uncertainty
M. Srivastava and J. H. Freed.
J. Phys. Chem. A 123, 359-370 (2019)
Supporting Information
<doi:10.1021/acs.jpca.8b07673>
PMID: 30525624      PMCID: PMC6372347
 

Cofactors are essential constituents of stable and seeding-active tau fibrils
Y. Fichou, Y. Lin, J. N. Rauch, M. Vigers, Z. Zeng, M. Srivastava, T. J. Keller, J. H. Freed, K. S. Kosik, and S. Han.
Proc. Natl. Acad. Sci. 115, 13234-13239 (2018)
Supporting Information
<doi:10.1073/pnas.1810058115>
PMID: 30538196      PMCID: PMC6310788
 

Phenyl-Ring Dynamics in Amyloid Fibrils and Proteins: The Microscopic-Order-Macroscopic-Disorder Perspective
E. Meirovitch, Z. Liang, and J. H. Freed.
J. Phys. Chem. B 122, 8675-8684 (2018)
Supporting Information
<doi:10.1021/acs.jpcb.8b06330>
PMID: 30141954      PMCID: PMC6174686
 

A facile approach for the in vitro assembly of multimeric membrane transport proteins
E. A. Riederer, P. J. Focke, E. R. Georgieva, N. Akyuz, K. Matulef, P. P. Borbat, J. H. Freed, S. C. Blanchard, O. Boudker, and F. I. Valiyaveetil.
eLife 7, e36478 (2018)
Supporting Information
<doi:10.7554/eLife.36478>
PMID: 29889023      PMCID: PMC6025958
 

Open and Closed Form of Maltose Binding Protein in Its Native and Molten Globule State As Studied by Electron Paramagnetic Resonance Spectroscopy
B. Selmke, P. P. Borbat, C. Nickolaus, R. Varadarajan, J. H. Freed, and W. E. Trommer.
Biochemistry 57, 5507-5512 (2018)
Supporting Information
<doi:10.1021/acs.biochem.8b00322>
PMID: 30004675      PMCID: PMC6211580
 

Site-Specific Incorporation of a Cu²⁺ Spin Label into Proteins for Measuring Distances by Pulsed Dipolar Electron Spin Resonance Spectroscopy
G. E. Merz, P. P. Borbat, A. R. Muok, M. Srivastava, D. N. Bunck, J. H. Freed, and B. R. Crane.
J. Phys. Chem. B 122, 9443-9451 (2018)
Supporting Information
<doi:10.1021/acs.jpcb.8b05619>
PMID: 30222354      PMCID: PMC6215709
 

MOMD Analysis of NMR Line Shapes from AΒ-Amyloid Fibrils: A New Tool for Characterizing Molecular Environments in Protein Aggregates
E. Meirovitch, Z. Liang, and J. H. Freed.
J. Phys. Chem. B 122, 4793-4801 (2018)
Supporting Information
<doi:10.1021/acs.jpcb.8b02181>
PMID: 29624402      PMCID: PMC5945340
 

Structural basis for membrane anchoring and fusion regulation of the herpes simplex virus fusogen gB
R. S. Cooper, E. R. Georgieva, P. P. Borbat, J. H. Freed, and E. E. Heldwein.
Nat. Struct. Mol. Biol. 25, 416-424 (2018)
Supporting Information
<doi:10.1038/s41594-018-0060-6>
PMID: 29728654      PMCID: PMC5942590
 

Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis
M. Dong, V. Kathiresan, M. K. Fenwick, A. T. Torelli, Y. Zhang, J. D. Caranto, B. Dzikovski, A. Sharma, K. M. Lancaster, J. H. Freed, S. E. Ealick, B. M. Hoffman, and H. Lin.
Science 359, 1247-1250 (2018)
Supporting Information
<doi:10.1126/science.aao6595>
PMID: 29590073      PMCID: PMC6066404
 

Protein dynamics in the solid-state from ²H NMR lineshape analysis. III. MOMD in the presence of Magic Angle Spinning
E. Meirovitch, Z. Liang, J. H. Freed.
Solid State Nucl. Magn. Reson. 89, 35-44 (2018)
<doi:10.1016/j.ssnmr.2017.11.001>
PMID: 29208317      PMCID: PMC5772661
 

Synthesis and Solution-Phase Characterization of Sulfonated Oligothioetheramides
J. S. Brown, Y. M. Acevedo, G. D. He, J. H. Freed, P. Clancy, and C. A. Alabi.
Macromolecules 50, 8731-8738 (2017)
Supporting Information
<doi:10.1021/acs.macromol.7b01915>
PMID: 29386690      PMCID: PMC5788177
 

Dipolar Spectroscopy — Single–Resonance Methods
P. P. Borbat and J. H. Freed.
In EPR Spectroscopy: Fundamentals and Methods. D. Goldfarb, and S. Stoll, Eds. 139, 15530-15538 (2017)
Wiley & Sons: Chichester, UK.
<doi:10.1002/9780470034590.emrstm1519>
PMID: [None - Book]      PMCID: [None - Book]
 

Design of Hydrated Porphyrin–Phospholipid Bilayers with Enhanced Magnetic Resonance Contrast
S. Shao, T. N. Do, A. Razi, U. Chitgupi, J. Geng, R. J. Alsop, B. G. Dzikovski, M. C. Rheinstädter, J. Ortega, M. Karttunen, J. A. Spernyak, and J. F. Lovell.
Small 13, 1602505 (2017).
Supporting Information
<doi:10.1002/smll.201602505>
PMID: 27739249      PMCID: PMC5209247
 

Singular Value Decomposition Method to Determine Distance Distributions in Pulsed Dipolar Electron Spin Resonance
M. Srivastava and J. H. Freed.
J. Phys. Chem. Lett. 8, 5648-5655 (2017)
Supporting Information
<doi:10.1021/acs.jpclett.7b02379>
PMID: 29099190      PMCID: PMC5708871
 

The SARS–CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium–Dependent Manner
A. L. Lai, J. K. Millet, S. Daniel, J. H. Freed, and G. R. Whittaker.
J. Mol. Biol. 429, 3875-3892 (2017)
<doi:10.1016/j.jmb.2017.10.017>
PMID: 29056462      PMCID: PMC5705393
 

Mechanistic Insight into the Photocontrolled Cationic Polymerization of Vinyl Ethers
Q. Michaudel, T. Chauviré, V. Kottisch, M. J. Supej, K. J. Stawiasz, L. Shen, W. R. Zipfel, H. D. Abruña, J. H. Freed, and B. P. Fors.
J. Am. Chem. Soc. 139, 15530-15538 (2017)
Supporting Information
<doi:10.1021/jacs.7b09539>
PMID: 28985061      PMCID: PMC5806523
 

Unique Structural Features of Membrane–Bound C–Terminal Domain Motifs Modulate Complexin Inhibitory Function
D. Snead, A. L. Lai, R. T. Wragg, D. A. Parisotto, T. F. Ramlall, J. S. Dittman, J. H. Freed, and D. Eliezer.
Front. Mol. Neurosci. 10, 154 (2017)
Supporting Information
<doi:10.3389/fnmol.2017.00154>
PMID: 28596722      PMCID: PMC5442187
 

Substrate–Dependent Cleavage Site Selection by Unconventional Radical S–Adenosylmethionine Enzymes in Diphthamide Biosynthesis
M. Dong, M. Horitani, B. Dzikovski, J. H. Freed, S. E. Ealick, B. M. Hoffman, and H. Lin.
J. Am. Chem. Soc. 139, 5680-5683 (2017)
Supporting Information
<doi:10.1021/jacs.7b01712>
PMID: 28383907      PMCID: PMC5664936
 

Key features of an Hsp70 chaperone allosteric landscape revealed by ion–mobility native mass spectrometry and double electron–electron resonance
A. L. Lai, E. M. Clerico, M. E. Blackburn, N. A. Patel, C. V. Robinson, P. P. Borbat, J. H. Freed, and L. M. Gierasch.
J. Biol. Chem. 292, 8773-8785 (2017)
Supporting Information
<doi:10.1074/jbc.M116.770404>
PMID: 28428246      PMCID: PMC5448104
 

A New Wavelet Denoising Method for Experimental Time–Domain Signals: Pulsed Dipolar Electron Spin Resonance
M. Srivastava, E. R. Georgieva, and J. H. Freed.
REFERENCE
Supporting Information
<doi:DOI>
PMID: PMID      PMCID: PMCID
 

Stability and Conformation of a Chemoreceptor HAMP Domain Chimera Correlates with Signaling Properties
N. Sukomon, J. Widom, P. P. Borbat, J. H. Freed, and B. R. Crane.
Biophys. J. 112, 1383-1395 (2017)
Supporting Information
<doi:10.1016/j.bpj.2017.02.037>
PMID: 28402881      PMCID: PMC5390053
 

Structure-Function Studies Link Class II Viral Fusogens with the Ancestral Gamete Fusion Protein HAP2
J. F. Pinello, A. L. Lai, J. K. Millet, D. Cassidy-Hanley, J. H. Freed, and T. G. Clark.
Curr. Biol. 27, 651-660 (2017)
Supporting Information
<doi:10.1016/j.cub.2017.01.049>
PMID: 28238660      PMCID: PMC5393271
 

Signature of an aggregation-prone conformation of tau
N. A. Eschmann, E. R. Georgieva, P. Ganguly, P. P. Borbat, M. D. Rappaport, Y. Akdogan, J. H. Freed, J. -E. Shea, and S. Han.
Sci. Rep. 7, 44739 (2017)
Supporting Information
<doi:10.1038/srep44739>
PMID: 28303942      PMCID: PMC5356194
 

Bacterial Energy Sensor Aer Modulates the Activity of the Chemotaxis Kinase CheA Based on the Redox State of the Flavin Cofactor
D. Samanta, J. Widom, P. P. Borbat, J. H. Freed, and B. R. Crane.
J. Biol. Chem. 291, 25809-25814 (2016)
<doi:10.1074/jbc.C116.757492>
PMID: 27803157      PMCID: PMC5207056
 

Nitrosomonas europaea cytochrome P460 is a direct link between nitrification and nitrous oxide emission
J. D. Caranto, A. C. Vilbert, and K. M. Lancaster.
Proc. Natl. Acad. Sci. 113, 14704-14709 (2016).
<doi:10.1073/pnas.1611051113>
PMID: 27856762      PMCID: PMC5187719
 

Organometallic Complex Formed by an Unconventional Radical S-Adenosylmethionine Enzyme
M. Dong, M. Horitani, B. Dzikovski, M. -E. Pandelia, C. Krebs, J. H. Freed, B. M. Hoffman, and H. Lin.
J. Am. Chem. Soc. 138, 9755-9758 (2016)
Supporting Information
<doi:10.1021/jacs.6b04155>
PMID: 27465315      PMCID: PMC5068486
 

A New Wavelet Denoising Method for Selecting Decomposition Levels and Noise Thresholds
M. Srivastava, C. L. Anderson, and J. H. Freed.
IEEE Access 4 3862-3877 (2016)
<doi:10.1109/ACCESS.2016.2587581>
PMID: 27795877      PMCID: PMC5079185
 

Constraints on the Radical Cation Center of Cytochrome c Peroxidase for Electron Transfer from Cytochrome c
T. M. Payne, E. F. Yee, B. Dzikovski, and B. R. Crane.
Biochemistry 55, 4807-4822 (2016).
<doi:10.1021/acs.biochem.6b00262>
PMID: 27499202      PMCID: PMC5689384
 

Conformational Response of Influenza A M2 Transmembrane Domain to Amantadine Drug Binding at Low pH (pH 5.5)
E. R. Georgieva, P. P. Borbat, K. Grushin, S. Stoilova-McPhie, N. J. Kulkarni, Z. Liang, and J. H. Freed.
Front. Physiol. 7, 317 (2016)
Supporting Information
<doi:10.3389/fphys.2016.00317>
PMID: 27524969      PMCID: PMC4965473
 

Local Ordering at Mobile Sites in Proteins from Nuclear Magnetic Resonance Relaxation: the Role of Site Symmetry
O. Tchaicheeyan, J. H. Freed, and E. Meirovitch.
J. Phys. Chem. B 120 2886-2898 (2016)
Supporting Information
<doi:10.1021/acs.jpcb.6b00524>
PMID: 26938937      PMCID: PMC4837759
 

Study of paramagnetic defect centers in as-grown and annealed TiO₂ anatase and rutile nanoparticles by a variable-temperature X-band and high-frequency (236 GHz) EPR
S. K. Misra, S. I. Andronenko, D. Tipikin, J. H. Freed, V. Somani, and O. Prakash.
J. Magn. Magn. Mater. 401, 495-505 (2016)
<doi:10.1016/j.jmmm.2015.10.072>
PMID: 27041794      PMCID: PMC4815036
 

Structural Basis for Activation, Assembly and Membrane Binding of ESCRT-III Snf7 Filaments
S. Tang, W. M. Henne, P. P. Borbat, N. J. Buchkovich, J. H. Freed, Y. Mao, J. C. Fromme, and S. D. Emr.
eLife 4 e12548 (2015)
Supporting Information
<doi:10.7554/eLife.12548>
PMID: 26670543      PMCID: PMC4720517
 

Pulsed Dipolar Spectroscopy Reveals that Tyrosyl Radicals Are Generated in Both Monomers of the Cyclooxygenase-2 Dimer
B. J. Orlando, P. P. Borbat, E. R. Georgieva, J. H. Freed, and M. G. Malkowski.
Biochemistry 54 7309-7312 (2015)
Supporting Information
<doi:10.1021/acs.biochem.5b00979>
PMID: 26636181      PMCID: PMC4707933
 

Protein Dynamics in the Solid State from ²H NMR Line Shape Analysis. II. MOMD Applied to C-D and C-CD₃ Probes
E. Meirovitch, Z. Liang, and J. H. Freed.
J. Phys. Chem. B 119 14022-14032 (2015)
<doi:10.1021/acs.jpcb.5b07434>
PMID: 26402431      PMCID: PMC4676681
 

Interaction of Spin-Labeled Lipid Membranes with Transition Metal Ions
B. Dzikovski, V. Livshits, and J.H. Freed
J. Phys. Chem. B 119, 13330-13346 (2015)
Supporting Information
<doi:10.1021/acs.jpcb.5b08165>
PMID: 26490692      PMCID: PMC4762260
 

Signal Transduction in Light-Oxygen-Voltage Receptors Lacking the Adduct-Forming Cysteine Residue
E.F. Yee, R.P. Diensthuber, A.T. Vaidya, P.P. Borbat, C. Engelhard, J.H. Freed, R. Bittl, A. Möglich, and B.R. Crane.
Nature Comm. 6 10079 (2015)
<doi:10.1038/ncomms10079>
PMID: 26648256      PMCID: PMC4682037
 

The Interaction between Influenza HA Fusion Peptide and Transmembrane Domain Affects Membrane Structure
A.L. Lai and J.H. Freed
Biophys. J. 109, 2523-2536 (2015)
<doi:10.1016/j.bpj.2015.10.044>
PMID: 26682811      PMCID: PMC4699882
 

Focus: Two-dimensional electron-electron double resonance and molecular motions: The challenge of higher frequencies
J.M. Franck, S. Chandrasekaran, B. Dzikovski, C.R. Dunnam, and J.H. Freed.
J. Chem. Phys. 142, 212302-212314 (2015).
<doi:10.1063/1.4917322>
PMID: 26049420      PMCID: PMC4443839
 

Preformed Soluble Chemoreceptor Trimers That Mimic Cellular Assembly States and Activate CheA Autophosphorylation
A.R. Greenswag, X. Li, P.P. Borbat, D. Samanta, K.J. Watts, J.H. Freed, and B.R. Crane
Biochemistry 54, 3454-3468 (2015).
Supporting Information
<doi:10.1021/bi501570n>
PMID: 25967982      PMCID: PMC4772074
 

Mechanism of Influenza A M2 Transmembrane Domain Assembly in Lipid Membranes
E.R. Georgieva, P.P. Borbat, H.D. Norman, and J.H. Freed
Sci. Rep. 5, 11757 (2015).
Supporting Information
<doi:10.1038/srep11757>
PMID: 26190831      PMCID: PMC4507135
 

Dynamic Nuclear Polarization of Membrane Proteins: Covalently Bound Spin-Labels at Protein-Protein Interfaces
B.J. Wylie, B.G. Dzikovski, S. Pawsey, M. Caporini, M. Rosay, J.H. Freed, A.E. McDermott.
J. Biomol. NMR 61, 361-367 (2015).
<doi:10.007/s10858-015-9919-6>
PMID: 25828256      PMCID: PMC4819240
 

Protein Dynamics in the Solid State from ²H NMR Line Shape Analysis: A Consistent Perspective
E. Meirovitch, Z. Liang, and J.H. Freed.
J. Phys. Chem B 119, 2857-2868 (2015).
<doi:10.1021/jp511386b>
PMID: 25594631      PMCID: PMC4358757
 

Assembly States of FliM and FliG Within the Flagellar Switch Complex
R. Sircar, P.P. Borbat, M.J. Lynch, J. Bhatnagar, M.S. Beyersdorf, C.J. Halkides, J.H. Freed and B.R. Crane.
J. Mol. Biol. 427, 867-886 (2015).
Supporting Information
<doi:10.1016/j.jmb.2014.12.009>
PMID: 25536293      PMCID: PMC4323944
 

Bacterial Chemoreceptor Dynamics Correlate With Activity State and Are Coupled Over Long Distances
D. Samanta, P.P. Borbat, B. Dzikovski, J.H. Freed, and B.R. Crane.
Proc. Natl. Acad. Sci. U. S. A. 112, 2455-2460 (2015).
Supporting Information
<doi:10.1073/pnas.1414155112>
PMID: 25675479      PMCID: PMC4345563
 

Pulse Dipolar ESR of Doubly Labeled Mini TAR DNA and Its Annealing to Mini TAR RNA
Y. Sun, P.P. Borbat, V.M. Grigoryants, W.K. Myers, J.H. Freed, and C.P. Scholes.
Biophys. J. 108, 893-902 (2015).
Supporting Information
<doi:10.1016/j.bpj.2014.12.028>
PMID: 25692594      PMCID: PMC4336369
 

Transport Domain Unlocking Sets the Uptake Rate of an Aspartate Transporter
N. Akyuz, E.R. Georgieva, Z. Zhou, S. Stolzenberg, M.A. Cuendet, G. Khelashvili, R.B. Altman, D.S. Terry, J.H. Freed, H. Weinstein, O. Boudker, and S.C. Blanchard.
Nature 518, 68-73 (2015).
<doi:10.1038/nature14158>
PMID: 25652997      PMCID: PMC4351760
 

A Fluorimetric Readout Reporting the Kinetics of Nucleotide-Induced Human Ribonucleotide Reductase Oligomerization
Y. Fu, H.-Y. Lin, S. Wisitpitthaya, W.A. Blessing and Y. Aye.
Chembiochem 15 2598-2604 (2014)
Supporting Information
<doi:10.1002/cbic.201402368>
PMID: 25256246      PMCID: PMC4271543
 

An Iron-Sulfur Cluster in the Polymerase Domain of Yeast DNA Polymerase ε
R. Jain, E.S. Vanamee, B.G. Dzikovski, A. Buku, R.E. Johnson, L. Prakash, S. Prakash, A.K. Aggarwal.
J. Mol. Biol. 426 301-308 (2014)
Supporting Information
<doi:10.1016/j.jmb.2013.10.015>
PMID: 24144619      PMCID: PMC4061903
 

Tau Binds to Lipid Membrane Surfaces via Short Amphipathic Helices Located in Its Microtubule-Binding Repeats
E.R. Georgieva, S. Xiao, P.P. Borbat, J.H. Freed, and D. Eliezer.
Biophys. J. 107, 1441-1452 (2014).
Supporting Information
<doi:10.1016/j.bpj.2014.07.046>
PMID: 25229151      PMCID: PMC4167292
 

Copper-Based Pulsed Dipolar ESR Spectroscopy as a Probe of Protein Conformation Linked to Disease States
G.E. Merz, P.P. Borbat, A.J. Pratt, E.D. Getzoff, J.H. Freed, and B.R. Crane.
Biophys. J. 107, 1669-1674 (2014).
Supporting Information
<doi:10.1016/j.bpj.2014.07.068>
PMID: 25296320      PMCID: PMC4190658
 

Aggregation Propensities of Superoxide Dismutase G93 Hotspot Mutants Mirror ALS Clinical Phenotypes
A.J. Pratt, D.S. Shin, G.E. Merz, R.P. Rambo, W.A. Lancaster, K.N. Dyer, P.P. Borbat, F.L. Poole II, M.W.W. Adams, J.H. Freed, B.R. Crane, J.A. Tainer, and E.D. Getzoff.
Proc. Natl. Acad. Sci. U. S. A. 111, E4568-E4576 (2014).
<doi:10.1073/pnas.1308531111>
PMID: 25316790      PMCID: PMC4217430
 

Dph3 Is an Electron Donor for Dph1-Dph2 in the First Step of Eukaryotic Diphthamide Biosynthesis
M. Dong, X. Su, B. Dzikovski, E.E. Dando, X. Zhu, J. Du, J.H. Freed, and H. Lin.
J. Am. Chem. Soc. 136, 1754-1757 (2014).
Supporting Information
<doi:10.1021/ja4118957>
PMID: 24422557      PMCID: PMC3985478
 

HIV gp41 Fusion Peptide Increases Membrane Ordering in a Cholesterol-Dependent Fashion
A.L. Lai and J.H. Freed.
Biophys. J. 106, 172-181 (2014).
<doi:10.1016/j.bpj.2013.11.027>
PMID: 24411249      PMCID: PMC3907210
 

Pulse Dipolar Electron Spin Resonance: Distance Measurements
P.P. Borbat and J.H. Freed.
In Structural Information from Spin-Labels and Intrinsic Paramagnetic Centers in the Biosciences. Structure and Bonding. Vol. 152. J. Harmer and C. Timmel, Eds.
Springer: Heidelberg, Germany; New York, USA, 2013; pp. 1-82.
<doi:10.1007/430_2012_82>
PMID: [None - Book]      PMCID: [None - Book]
 

Uncoupling of Allosteric and Oligomeric Regulation in a Functional Hybrid Enzyme Constructed from Escherichia coli and Human Ribonucleotide Reductase
Y. Fu, M.J.C. Long, M. Rigney, S. Parvez, W.A. Blessing, Y. Aye.
Biochemistry 52 7050-7059 (2013)
Supporting Information
<doi:10.1021/bi400781z>
PMID: 24024562     
 

Architecture of the Soluble Receptor Aer2 Indicates an In-Line Mechanism for PAS and HAMP Domain Signaling
M.V. Airola, D. Huh, N. Sukomon, J. Widom, R. Sircar, P.P. Borbat, J.H. Freed, K.J. Watts, and B.R. Crane.
J. Mol. Biol. 425, 886-901 (2013).
Supporting Information
<doi:10.1016/j.jmb.2012.12.011>
PMID: 23274111      PMCID: PMC3577987
 

HAMP Domain Conformers that Propagate Opposite Signals in Bacterial Chemoreceptors
M.V. Airola, N. Sukomon, D. Samanta, P.P. Borbat, J.H. Freed, K.J. Watts, and B.R. Crane.
PLoS Biol. 11, e1001479, (2013).
Supporting Information
<doi:10.1371/journal.pbio.1001479>
PMID: 23424282      PMCID: PMC3570549
 

Improved Sensitivity for Long-Distance Measurements in Biomolecules: Five-Pulse Double Electron-Electron Resonance
P.P. Borbat, E.R. Georgieva, and J.H. Freed.
J. Phys. Chem. Lett. 4, 170-175 (2013).
Supporting Information
<doi:10.1021/jz301788n>
PMID: 23301118      PMCID: PMC3538160
 

Spin Labels in the Gel Phase and Frozen Lipid Bilayers: Do They Truly Manifest a Polarity Gradient?
B. Dzikowski and J.H. Freed.
In Nitroxides-Theory, Experiment and Applications; A. Kokorin. Ed.
InTech: Rijeka, Croatia, 2012; pp. 167-190.
<doi:10.5772/2887>
PMID: [None - Book]      PMCID: [None - Book]
 

The Internal Dynamics of Mini c TAR DNA Probed by Electron Paramagnetic Resonance of Nitroxide Spin-Labels at the Lower Stem, the Loop, and the Bulge
Y. Sun, Z. Zhang, V.M. Grigoryants, W.K. Myers, F. Liu, and K. Earle, J.H. Freed, C.P. Scholes
Biochemistry 51, 8530-8541 (2012).
Supporting Information
<doi:10.1021/bi301058q>
PMID: 23009298      PMCID: PMC3549007
 

Conformational Ensemble of the Sodium-Coupled Aspartate Transporter
E.R. Georgieva, P.P. Borbat, C. Ginter, J.H. Freed, and O. Boudker.
Nat. Struct. Mol. Biol. 20, 215-221 (2013).
Supporting Information
<doi:10.1038/nsmb.2494>
PMID: 23334289      PMCID: PMC3565060
 

Locating a Lipid at the Portal to the Lipoxygenase Active Site
B.J. Gaffney, M. Bradshaw, S. Frausto, F. Wu, J.H. Freed, and P.P. Borbat.
Biophysical J. 103, 2134-2144, (2012).
Supporting Information
<doi:10.1016/j.bpj.2012.10.002>
PMID: 23200047      PMCID: PMC3512035
 

Pulsed ESR Dipolar Spectroscopy for Distance Measurements in Immobilized Spin Labeled Proteins in Liquid Solution
Z. Yang, Y. Liu, P.P. Borbat, J.L. Zweier, J.H. Freed, and W.L. Hubbell.
J. Am. Chem. Soc. 134, 9950-9952 (2012).
Supporting Information
<doi:10.1021/ja303791p>
PMID: 22676043      PMCID: PMC3409244
 

Self-Association of the Histidine Kinase CheA as Studied by Pulsed Dipolar ESR Spectroscopy
J. Bhatnagar, R. Sircar, P.P. Borbat, J.H. Freed, and B.R. Crane.
Biophys. J. 102, 2192-2201 (2012).
Supporting Information
<doi:10.1016/j.bpj.2012.03.038>
PMID: 22824284      PMCID: PMC3341552
 

Dynamics and Ordering of Lipid Spin-Labels Along the Coexistence Curve of Two Membrane Phases: An ESR Study
A.K. Smith and J.H. Freed.
Chem. Phys. Lipids, 165, 348-361 (2012).
Supporting Information
<doi:10.1016/j.chemphyslip.2012.02.009>
PMID: 22586732      PMCID: PMC3526980
 

Conformational Distributions and Hydrogen Bonding in Gel and Frozen Lipid Bilayers: A High Frequency Spin-Label ESR Study
B. Dzikovski, D. Tipikin, and J. Freed
J. Phys. Chem. B, 116, 6694-6706 (2012).
Supporting Information
<doi:10.1021/jp211879s>
PMID: 22324811      PMCID: PMC3376253
 

Effect of Freezing Conditions on Distances and Their Distributions Derived From Double Electron Electron Resonance (DEER): A Study of Doubly-Spin-Labeled T4 Lysozyme
E.R. Georgieva, A.S. Roy, V.M. Grigoryants, P.P. Borbat, K.A. Earle, C.P. Scholes, and J.H. Freed.
J. Magn. Reson. 216, 69-77 (2012).
Supporting Information
<doi:10.1016/j.jmr.2012.01.004>
PMID: 22341208      PMCID: PMC3323113
 

A Protocol for Detecting and Scavenging Gas-phase Free Radicals in Mainstream Cigarette Smoke
L.X. Yu, B.G. Dzikovski, and J.H. Freed.
J. Vis. Exp. 59, e3406 (2012).
<doi:10.3791/3406>
PMID: 22230844      PMCID: PMC3369772
 

Electron Tunneling in Lithium-Ammonia Solutions Probed by Frequency-Dependent Electron Spin Relaxation Studies
K. Maeda, M.T.J. Lodge, J. Harmer, J.H. Freed, and P.P. Edwards.
J. Am. Chem. Soc. 134, 9209-18 (2012).
<doi:10.1021/ja212015b>
PMID: 22568866      PMCID: PMC3415590
 

Membrane Fluidity
B. Dzikovski and J.H. Freed.
In Encyc. Biophys.; G.C.K. Roberts, Ed.
Springer Verlag: Berlin, Germany, 2013; pp 1440-1446.
<doi:10.1007/978-3-642-16712-6_546>
PMID: [None - Book]      PMCID: [None - Book]
 

Stochastic Methods for Magnetic Resonance Spectroscopies
A. Polimeno, V. Barone, and J.H. Freed.
In Computational Strategies for Spectroscopy: From Small Molecules to Nano Systems; V. Barone, Ed.
Wiley: New York, NY, 2012; Chapter 12.
PMID: [None - Book]      PMCID: [None - Book]
 

Protein Dynamics by NMR Spin Relaxation: The Slowly Relaxing Local Structure Perspective
E. Meirovitch, A. Polimeno, and J.H. Freed.
In E. Mag. Res. Online, R.K. Harris and R.L. Wasylishen, Eds.
John Wiley & Sons, Inc.: New York, 2011; pp 1-9.
<doi:10.1002/9780470034590.emrstm1243>
PMID: [None - Book]      PMCID: [None - Book]
 

Distance Measurements: Continuous-Wave (CW)- and Pulsed Dipolar EPR
S.K. Misra and J.H. Freed.
In Multifrequency Electron Paramagnetic Resonance, S.K. Misra, Ed.
Wiley-VCH: New York, 2011; Chapter 12, pp. 545-588.
PMID: [None - Book]      PMCID: [None - Book]
 

Molecular Motions
S.K. Misra and J.H. Freed.
In Multifrequency Electron Paramagnetic Resonance, S.K. Misra, Ed.
Wiley-VCH: New York, 2011; Chapter 11, pp. 497-544.
PMID: [None - Book]      PMCID: [None - Book]
 

2D-ELDOR Study of Heterogeneity and Domain Structure Changes in Plasma Membrane Vesicles upon Cross-Linking of Receptors
Y.-W. Chiang, A.J. Costa-Filho, B. Baird, and J.H. Freed.
J. Phys. Chem. B 115, 10462-10469 (2011).
Supporting Information
<doi:10.1021/jp2016243>
PMID: 21780815      PMCID: PMC3165081
 

Mechanistic Understanding of Pyrococcus horikoshii Dph2, a [4Fe-4S] Enzyme Required for Diphthamide Biosynthesis
X. Zhu, B. Dzikovski, X. Su, A.T. Torelli, Y. Zhang, S.E. Ealick, J.H. Freed and H. Lin.
Mol. Biosyst. 7, 74-81 (2011).
<doi:10.1039/c0mb00076k>
PMID: 20931132      PMCID: PMC3066188
 

A New Lanczos-Based Algorithm for Simulating High-Frequency Two-Dimensional Electron Spin Resonance Spectra
Y.-W. Chiang and J.H. Freed.
J. Chem. Phys. 134, 034112 (2011).
<doi:10.1063/1.3523576>
PMID: 21261335      PMCID: PMC3041155
 

Joint Analysis of ESR Lineshapes and ¹H NMRD Profiles of DOTA-Gd Derivatives by Means of the Slow Motion Theory
D. Kruk, J. Kowalewski, D.S. Tipikin, J.H. Freed, M. Mościcki, A. Mielczarek, and M. Port.
J. Chem. Phys. 134, 024508 (2011).
<doi:10.1063/1.3516590>
PMID: 21241121      PMCID: PMC3188623
 

Methyl Dynamics of a Ca²⁺-Calmodulin-Peptide Complex from NMR/SRLS
Y.E. Shapiro, A. Polimeno, J.H. Freed, and E. Meirovitch.
J. Phys. Chem. B 115, 354-365 (2011).
<doi:10.1021/jp107130m>
PMID: 21166433      PMCID: PMC3062514
 

ESR Microscopy for Biological and Biomedical Applications
C.S. Shin, C.R. Dunnam, P.P. Borbat, B. Dzikovski, E.D. Barth, H.J. Halpern, and J.H. Freed.
Nanoscience & Nanotechnology Letters 3, 561-567 (2011).
<doi:10.1166/nnl.2011.1206>
PMID: 21984955      PMCID: PMC3188420
 

Backbone Dynamics of Deoxy and Carbonmonoxy Hemoglobin by NMR/SRLS
E. Meirovitch, M. Zerbetto, A. Polimeno, and J.H. Freed.
J. Phys. Chem. B 115, 143-157 (2011).
<doi:10.1021/jp107553j>
PMID: 21162544      PMCID: PMC3071157
 

Two Conserved Residues Are Important for Inducing Highly Ordered Membrane Domains by the Transmembrane Domain of Influenza Hemagglutinin
M. Ge and J.H. Freed.
Biophys. J. 100, 90-97 (2011).
Supporting Information
<doi:10.1016/j.bpj.2010.11.014>
PMID: 21190660      PMCID: PMC3010018
 

Channel and Nonchannel Forms of Spin-Labeled Gramicidin in Membranes and Their Equilibria
B.G. Dzikovski, P.P. Borbat, and J.H. Freed.
J. Phys. Chem. B 115, 176-185 (2011).
Supporting Information
<doi:10.1021/jp108105k>
PMID: 21142163      PMCID: PMC3076037